Data in support of substrate flexibility of a mutated acyltransferase domain and implications for polyketide biosynthesis

Data in support of substrate flexibility of a mutated acyltransferase domain and implications for polyketide biosynthesis

Enzyme-directed mutasynthesis is an emerging strategy for the targeted derivatization of natural products. Here, data on the synthesis of malonic acid derivatives for feeding studies in Saccharopolyspora erythraea , the mutagenesis of DEBS and bioanalytical data on the experimental investigation of...

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Bibliographic Details
Published in:Data in brief Vol. 5; no. C; pp. 528 - 536
Main Authors: Klopries, Stephan, Bravo-Rodriguez, Kenny, Koopmans, Kyra R.M., Sundermann, Uschi, Yahiaoui, Samir, Arens, Julia, Kushnir, Susanna, Sanchez-Garcia, Elsa, Schulz, Frank
Format: Journal Article
Language:English
Published: Netherlands Elsevier Inc 01-12-2015
Elsevier
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Data
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Summary:Enzyme-directed mutasynthesis is an emerging strategy for the targeted derivatization of natural products. Here, data on the synthesis of malonic acid derivatives for feeding studies in Saccharopolyspora erythraea , the mutagenesis of DEBS and bioanalytical data on the experimental investigation of studies on the biosynthetic pathway towards erythromycin are presented.
ISSN:2352-3409
2352-3409
DOI:10.1016/j.dib.2015.09.052