An evaluation of thyrotoxic autoimmune thyroiditis patients with triplex Doppler ultrasonography

• Published in: Clinical imaging Vol. 38; no. 1; pp. 1 - 5
• Main Authors: Karakas, Omer, Karakas, Ekrem, Cullu, Nesat, Demir, Yusuf, Kucukyavas, Yasin, Surucu, Erdem, Yener, Serkan, Igci, Enis
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01-01-2014; Elsevier Limited
• Subjects: Adult; Area Under Curve; Autoimmune thyroiditis; Cardiovascular disease; Common carotid artery; Confidence intervals; Cross-Sectional Studies; Drug therapy; Female; Hormone replacement therapy; Humans; Hyperthyroidism; Male; Methods; Middle Aged; Organ Size; Radiology; Radionuclide Imaging; Regional Blood Flow; Superior thyroid artery; Thyroid Gland - blood supply; Thyroid Gland - diagnostic imaging; Thyroid Gland - pathology; Thyroiditis, Autoimmune - complications; Thyroiditis, Autoimmune - diagnostic imaging; Thyrotoxicosis - complications; Thyrotoxicosis - diagnostic imaging; Triplex Doppler ultrasonography; Ultrasonography, Doppler; superior thyroid artery; STA; 24-h radioactive iodine uptake; Group 2; end-diastolic velocity; Group 1; Group 3; 24-h RAIU; thyroid-stimulating hormones; HT; resistive index ratio; common carotid artery; TPOAb; peak systolic velocity; Triplex Doppler ultrasonography; TSH receptor autoantibodies; patients with BGD; EDV; free thyroxine; TRAb; resistive index; PSVR; healthy controls; BGD; CCA; peak systolic velocity ratio; FT3; inferior thyroid artery; thyroglobulin antibodies; FT4; free triiodothyronine; TSH; patients with HT; thyroid peroxidase antibodies; 4-h radioactive iodine uptake; PSV; Basedow–Graves disease; TgAb; Hashimoto thyroiditis; RI; end-diastolic velocity ratio; ITA; RIR; EDVR; 4-h RAI4; Autoimmune thyroiditis; Common carotid artery; Superior thyroid artery
• ISSN: 0899-7071; 1873-4499
• DOI: 10.1016/j.clinimag.2013.06.010

Abstract Objective This study aimed to investigate the usefulness of blood flow parameters obtained from STA and CCA with Triplex Doppler ultrasonography (TDU) on patients with thyrotoxicosis. Materials and methods This cross-sectional study included consecutive 24 patients with thyrotoxicosis and 18 healthy controls. The thyroid gland blood flow parameters were evaluated with TDU. Results The thyroid volumes and FT3, TRAb, 4-h and 24-h radioactive iodine uptake (RAIU) levels of Group 1 were significantly high compared to those of Group 2. The thyroid volumes and FT3, FT4 and TSH levels of both Group 1 and Group 2 showed a statistically significant difference compared to Group 3. STA–PSV values for Group 1, Group 2 and Group 3 were 138 cm/s, 54 cm/s and 37 cm/s, respectively. STA–EDV values for these groups were 60 cm/s, 25 cm/s and 15 cm/s, respectively. PSVR values for these groups were 1.01, 0.45, 0.34 cm/s, respectively. EDVR values for these groups were 1.29, 0.70 and 0.49 cm/s, respectively. In Group 1, STA–PSV, STA–EDV, PSVR and EDVR values were significantly high compared to those of Group 2. RAIU levels showed a significant positive correlation with the STA–PSV, STA–EDV and PSVR. Conclusion The thyroid gland blood flow parameters may be used in clinical diagnosis of patients with thyrotoxicosis.