Cell Division: Single-Cell Physiology Reveals Secrets of Chromosome Condensation

Our understanding of higher order chromosome structure has been transformed through statistical mechanics-based computer simulations of polymer chains. A new study exploring basic electrostatic interactions demystifies how chromosomes regulate their state of compaction over several orders of magnitu...

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Bibliographic Details
Published in:Current biology Vol. 28; no. 3; pp. R117 - R119
Main Author: Bloom, Kerry
Format: Journal Article
Language:English
Published: England Elsevier Inc 05-02-2018
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Summary:Our understanding of higher order chromosome structure has been transformed through statistical mechanics-based computer simulations of polymer chains. A new study exploring basic electrostatic interactions demystifies how chromosomes regulate their state of compaction over several orders of magnitude. Our understanding of higher order chromosome structure has been transformed through statistical mechanics-based computer simulations of polymer chains. A new study exploring basic electrostatic interactions demystifies how chromosomes regulate their state of compaction over several orders of magnitude.
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ISSN:0960-9822
1879-0445
DOI:10.1016/j.cub.2017.12.032