Bloodborne viral infections: Seroprevalence and relevance of preoperative screening in Indian eye care system - A retrospective study

• Published in: Indian journal of ophthalmology Vol. 72; no. 2; pp. 258 - 263
• Main Authors: Gangwe, Anil B, Chatterjee, Samrat, Singh, Abhishek, Agrawal, Deepshikha, Rahangdale, Diksha, Azad, Raj Vardhan
• Format: Journal Article
• Language: English
• Published: India Medknow Publications and Media Pvt. Ltd 01-02-2024; Medknow Publications & Media Pvt. Ltd; Wolters Kluwer Medknow Publications
• Subjects: bloodborne viral infections; eye care; Feasibility studies; Hepatitis; Hepatitis B; Hepatitis C; Hepatitis C virus; HIV; HIV (Viruses); Human immunodeficiency virus; india; Infection; Infections; Medical personnel; Medical research; Medicine, Experimental; needle stick injury; ophthalmology; Patients; preoperative screening; Seroconversion; Serology; Statistical analysis; Surgery; universal safety precautions; Viral infections; viral markers; Viruses; India
• ISSN: 0301-4738; 1998-3689
• DOI: 10.4103/IJO.IJO_958_23

To report the seroprevalence of bloodborne viral infection (BBVI) in patients undergoing ophthalmic surgeries and assess the utility and feasibility of preoperative screening for BBVI in India's current eye care system.
This retrospective, hospital-based, descriptive study included data from patients undergoing preoperative screening for Hepatitis B virus (HBV), Hepatitis C virus (HCV), and human immunodeficiency virus (HIV) at a tertiary eye care institute from 2018 to 2022. Rapid diagnostic tests (RDTs) were performed on the blood samples after obtaining informed consent from the patients. Seroreactive patients underwent surgery with additional safety precautions. The demographic data and surgical details of these patients were collected and analyzed. ANOVA was used to carry out statistical analysis between groups. During the study period, the number of healthcare workers (HCWs) sustaining needle stick injury (NSI) and accidental sharp injury (ASI) in the operating theater (OT) and details of these injuries were recorded.
Samples from 28,563 patients were included. The seroprevalence of BBVI was 1.87% (536/28563). Hepatitis B virus (322, 60.1%) was the most commonly detected infection, and HIV (59, 11%) was the least detected infection. The mean age of the seroreactive patients was 60.3 ± 30.8 years. The incidence of NSI was 0.49/1000 surgeries. Nurses (11) and technicians (4) in the OT sustained maximum NSI. None of the HCWs had seroconversion after NSI.
The overall seroprevalence of BBVI in the current study is lower than that reported in previously published studies from eye care organizations. Currently, mandatory preoperative screening for BBVI to prevent transmission of these infections to HCWs working in the eye care sector in India appears to be less cost-effective.