Antisynthethase syndrome presenting as peripheral limb fasciitis

Abstract Inflammatory myopathy is a major clinical manifestation of the antisynthetase syndrome. Patients with anti Jo-1 antibodies can also present with other clinical manifestations as arthritis, mechanic's hands and lung fibrosis. As in dermatomyositis, polymyositis and overlap myopathies pr...

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Bibliographic Details
Published in:Joint, bone, spine : revue du rhumatisme Vol. 80; no. 5; pp. 528 - 530
Main Authors: Ebbo, Mikael, Chagnaud, Christophe, Figarella-Branger, Dominique, Legall, Stevan, Harle, Jean-Robert, Schleinitz, Nicolas
Format: Journal Article
Language:English
Published: France Elsevier SAS 01-10-2013
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Summary:Abstract Inflammatory myopathy is a major clinical manifestation of the antisynthetase syndrome. Patients with anti Jo-1 antibodies can also present with other clinical manifestations as arthritis, mechanic's hands and lung fibrosis. As in dermatomyositis, polymyositis and overlap myopathies proximal muscle of the limbs are preferentialy involved. Associated fascia edema on magnetic resonance imagery studies with histological proven fasciitis has been reported. However peripheral limb involvement, reported here in two patients, as the isolated initial manifestation is unusual.
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ISSN:1297-319X
1778-7254
DOI:10.1016/j.jbspin.2013.02.013