A fully-coupled fluid-structure interaction simulation of cerebral aneurysms

• Published in: Computational mechanics Vol. 46; no. 1; pp. 3 - 16
• Main Authors: Bazilevs, Y., Hsu, M.-C., Zhang, Y., Wang, W., Liang, X., Kvamsdal, T., Brekken, R., Isaksen, J. G.
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer-Verlag 01-06-2010; Springer; Springer Nature B.V; Springer Berlin/Heidelberg
• Subjects: Aneurysms; Bifurcations; Blood flow; Cardiology: 771; Classical and Continuum Physics; Clinical medical disciplines: 750; Comparative analysis; Computational Science and Engineering; Computer simulation; Engineering; Finite element method; Fluid-structure interaction; Hemodynamics; Kardiologi: 771; Klinisk medisinske fag: 750; Medical disciplines: 700; Medisinske Fag: 700; Mesh generation; Original Paper; Theoretical and Applied Mechanics; VDP; Wall shear stresses; Boundary layer meshing; Cerebral aneurysms; Incompressible Navier–Stokes equations; Arterial wall tissue modeling; Wall shear stress; Wall tension; Fluid-structure interaction
• ISSN: 0178-7675; 1432-0924
• DOI: 10.1007/s00466-009-0421-4

This paper presents a computational vascular fluid-structure interaction (FSI) methodology and its application to patient-specific aneurysm models of the middle cerebral artery bifurcation. A fully coupled fluid-structural simulation approach is reviewed, and main aspects of mesh generation in support of patient-specific vascular FSI analyses are presented. Quantities of hemodynamic interest such as wall shear stress and wall tension are studied to examine the relevance of FSI modeling as compared to the rigid arterial wall assumption. We demonstrate the importance of including the flexible wall modeling in vascular blood flow simulations by performing a comparison study that involves four patient-specific models of cerebral aneurysms varying in shape and size.