Moving a missing hand: children born with below elbow deficiency can enact hand grasp patterns with their residual muscles

• Published in: Journal of neuroengineering and rehabilitation Vol. 21; no. 1; pp. 13 - 15
• Main Authors: Fitzgerald, Justin J, Battraw, Marcus A, James, Michelle A, Bagley, Anita M, Schofield, Jonathon S, Joiner, Wilsaan M
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 23-01-2024; BioMed Central; BMC
• Subjects: Abnormalities; Activities of daily living; Adult; Age; Algorithms; Arm; Bones; Care and treatment; Causes of; Child; Children; Children & youth; Elbow; Elbow Joint; Extremities, Upper; Hand; Humans; Informed consent; Limbs; Machine learning; Motor ability; Motor task performance; Movement disorders; Muscles; Pattern recognition; Pediatric research; Pediatrics; Physiological aspects; Prostheses; Prosthetics; Sensorimotor system; Ultrasonic imaging; Upper Extremity; United States
• ISSN: 1743-0003; 1743-0003
• DOI: 10.1186/s12984-024-01306-z

Children with a unilateral congenital below elbow deficiency (UCBED) have one typical upper limb and one that lacks a hand, ending below the elbow at the proximal/mid forearm. UCBED is an isolated condition, and affected children otherwise develop normal sensorimotor control. Unlike adults with upper limb absence, the majority of whom have an acquired loss, children with UCBED never developed a hand, so their residual muscles have never actuated an intact limb. Their ability to purposefully modulate affected muscle activity is often assumed to be limited, and this assumption has influenced prosthetic design and prescription practices for this population as many modern devices derive control signals from affected muscle activity. To better understand the motor capabilities of the affected muscles, we used ultrasound imaging to study 6 children with UCBED. We examined the extent to which subjects activate their affected muscles when performing mirrored movements with their typical and missing hands. We demonstrate that all subjects could intentionally and consistently enact at least five distinct muscle patterns when attempting different missing hand movements (e.g., power grasp) and found similar performance across affected and typically developed limbs. These results suggest that although participants had never actuated the missing hand they could distinctively and consistently activate the residual muscle patterns associated with actions on the unaffected side. These findings indicate that motor control still develops in the absence of the normal effector, and can serve as a guide for developing prostheses that leverage the full extent of these children's motor control capabilities.