Status epilepticus: Using antioxidant agents as alternative therapies

• Published in: Experimental and therapeutic medicine Vol. 12; no. 4; pp. 1957 - 1962
• Main Authors: Carmona-Aparicio, Liliana, Zavala-Tecuapetla, Cecilia, González-Trujano, María Eva, Sampieri, Aristides Iii, Montesinos-Correa, Hortencia, Granados-Rojas, Leticia, Floriano-Sánchez, Esaú, Coballase-Urrutía, Elvia, Cárdenas-Rodríguez, Noemí
• Format: Journal Article
• Language: English
• Published: Greece D.A. Spandidos 01-10-2016; Spandidos Publications; Spandidos Publications UK Ltd
• Subjects: Alternative medicine; antioxidant agents; Antioxidants; Antioxidants (Nutrients); Care and treatment; Consciousness; Dosage and administration; Epilepsy; epileptic state; Medical research; Metabolism; Oxidative stress; Patients; Physiology; Review; Rodents; Status epilepticus; Studies; Trauma; epilepsy; antioxidant agents; oxidative stress; epileptic state
• ISSN: 1792-0981; 1792-1015
• DOI: 10.3892/etm.2016.3609

The epileptic state, or status epilepticus (SE), is the most serious situation manifested by individuals with epilepsy, and SE events can lead to neuronal damage. An understanding of the molecular, biochemical and physiopathological mechanisms involved in this type of neurological disease will enable the identification of specific central targets, through which novel agents may act and be useful as SE therapies. Currently, studies have focused on the association between oxidative stress and SE, the most severe epileptic condition. A number of these studies have suggested the use of antioxidant compounds as alternative therapies or adjuvant treatments for the epileptic state.