Genetically Engineered Peptides for Inorganics: Study of an Unconstrained Bacterial Display Technology and Bulk Aluminum Alloy

The first‐ever peptide biomaterial discovery using an unconstrained engineered bacterial display technology is reported. Using this approach, we have developed genetically engineered peptide binders for a bulk aluminum alloy and use molecular dynamics simulation of peptide conformational fluctuation...

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Bibliographic Details
Published in:	Advanced materials (Weinheim) Vol. 25; no. 33; pp. 4585 - 4591
Main Authors:	Adams, Bryn L., Finch, Amethist S., Hurley, Margaret M., Sarkes, Deborah A., Stratis-Cullum, Dimitra N.
Format:	Journal Article
Language:	English
Published:	Weinheim WILEY-VCH Verlag 06-09-2013 WILEY‐VCH Verlag
Subjects:	Alloys - chemistry Aluminum - chemistry Bacteria biomineralization biopanning Communications Escherichia coli - genetics Genetic Engineering GEPI molecular dynamics peptide display Peptide Library Peptides - chemistry Peptides - genetics solid-binding peptide Surface Properties solid-binding peptide biopanning peptide display biomineralization molecular dynamics GEPI
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Summary:	The first‐ever peptide biomaterial discovery using an unconstrained engineered bacterial display technology is reported. Using this approach, we have developed genetically engineered peptide binders for a bulk aluminum alloy and use molecular dynamics simulation of peptide conformational fluctuations to demonstrate sequence‐dependent, structure‐function relationships for metal and metal oxide interactions.
Bibliography:	istex:6B635BF5EE784A7C5B234EED5AD62CAF134C2A80 ArticleID:ADMA201301646 ark:/67375/WNG-0P57MLP7-1 ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0935-9648 1521-4095
DOI:	10.1002/adma.201301646