Gold-Gold Cooperation in the Addition of Methanol to Alkynes

Gold-Gold Cooperation in the Addition of Methanol to Alkynes

The gold(I)‐mediated reaction between an internal alkyne and methanol proceeds by a dual activation mechanism, which directly results in formation of gem‐diaurated intermediates. Reaction intermediates were investigated by IR multiphoton dissociation spectroscopy, kinetics by NMR spectroscopy, and t...

Full description

Saved in:
Bibliographic Details
Published in:Angewandte Chemie International Edition Vol. 51; no. 33; pp. 8378 - 8382
Main Authors: Roithova, Jana, Jankova, Stpánka, Jasikova, Lucie, Vaa, Jirí, Hybelbauerova, Simona
Format: Journal Article
Language:English
Published: Weinheim WILEY-VCH Verlag 13-08-2012
WILEY‐VCH Verlag
Wiley Subscription Services, Inc
Edition:International ed. in English
Subjects:
Activation
Alkynes
Alkynes - chemistry
Catalysis
Cooperation
density functional calculations
Formations
Gold
Gold - chemistry
gold catalysis
Infrared radiation
ion spectroscopy
kinetics
Mathematical analysis
Methanol - chemistry
Methyl alcohol
NMR spectroscopy
Organogold Compounds - chemical synthesis
Organogold Compounds - chemistry
reaction intermediates
Spectroscopy
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The gold(I)‐mediated reaction between an internal alkyne and methanol proceeds by a dual activation mechanism, which directly results in formation of gem‐diaurated intermediates. Reaction intermediates were investigated by IR multiphoton dissociation spectroscopy, kinetics by NMR spectroscopy, and the mechanism by DFT calculations.
Bibliography:ark:/67375/WNG-4XXZCW25-Z
European Research Council
The authors gratefully acknowledge financial support from the Grant agency of the Czech Republic (207/11/0338), the European Research Council (StG ISORI) and the Ministry of Education of the Czech Republic (MSM0021620857). The results from CLIO were obtained thanks to the funding from the European Union's Seventh Framework Programme (FP7/2007-2013) under grant agreement no. 226716. The CLIO staff, particularly Vincent Steinmetz, are gratefully acknowledged for their help and assistance. We thank Zdeněk Tošner for helping with the NMR spectra acquisition.
Ministry of Education of the Czech Republic - No. MSM0021620857
ArticleID:ANIE201204003
Grant agency of the Czech Republic - No. 207/11/0338
European Union - No. 226716
istex:0C150BAEBBA3B64F267177065DFB81E3E36D13D1
The authors gratefully acknowledge financial support from the Grant agency of the Czech Republic (207/11/0338), the European Research Council (StG ISORI) and the Ministry of Education of the Czech Republic (MSM0021620857). The results from CLIO were obtained thanks to the funding from the European Union’s Seventh Framework Programme (FP7/2007‐2013) under grant agreement no. 226716. The CLIO staff, particularly Vincent Steinmetz, are gratefully acknowledged for their help and assistance. We thank Zdeněk Tošner for helping with the NMR spectra acquisition.
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.201204003