The pharmacology and clinical use of methotrexate

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Bibliographic Details
Published in:	The New England journal of medicine Vol. 309; no. 18; p. 1094
Main Authors:	Jolivet, J, Cowan, K H, Curt, G A, Clendeninn, N J, Chabner, B A
Format:	Journal Article
Language:	English
Published:	United States 03-11-1983
Subjects:	Administration, Oral Animals Biological Transport - drug effects Central Nervous System - metabolism Drug Resistance Folic Acid - metabolism Folic Acid Antagonists Gene Amplification Head and Neck Neoplasms - drug therapy Humans Kinetics Leucovorin - administration & dosage Leukemia, Lymphoid - drug therapy Lung Neoplasms - drug therapy Methotrexate - metabolism Methotrexate - pharmacology Methotrexate - therapeutic use Neoplasms - drug therapy Neoplasms - enzymology Osteoma, Osteoid - drug therapy Thymidylate Synthase - metabolism Tissue Distribution
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ISSN:	0028-4793
DOI:	10.1056/NEJM198311033091805