Autopsies and quality of cause of death diagnoses

• Published in: SAGE open medicine Vol. 9; p. 20503121211037169
• Main Authors: Rosendahl, Anders, Mjörnheim, Berit, Eriksson, Lennart C
• Format: Journal Article
• Language: English
• Published: London, England SAGE Publications 2021; Sage Publications Ltd; SAGE Publishing
• Subjects: Autopsies; Original; autopsy and level of care; clinical autopsy; age dependence; Autopsy; death certificate errors; cause of death; forensic autopsy; gender differences
• ISSN: 2050-3121; 2050-3121
• DOI: 10.1177/20503121211037169

Objective:
The consequences of a low autopsy rate are not considered in determining the cause of death.
Method:
We have analyzed the Cause of Death Register of the Swedish National Board of Health and Welfare since it started 1969 to and including 2016 to visualize the decline in the frequency of clinical autopsies over time and evaluated the effect on the quality of the cause of death diagnoses.
Results:
Over the five decades studied, the frequency of clinical autopsies declined from almost 40% to less than 5%. The rate of decline was not even. Political decisions and changes of healthcare organization in Sweden affected the slope of decline of autopsies superimposed on a linear decline over time reflecting changes in clinical routines. A request of clinical autopsies was highly dependent on the level of care at the time of death, with the lowest number of requests for persons who died in nursing homes. The age at the time of death was a major factor affecting the number of autopsies, resulting in an autopsy rate of less than 1% in the ages where most persons die. Although men were autopsied more often than women, a gender-specific difference was not seen after correction for the age of death. We also found a higher rate of unspecific and irrelevant diagnosis in the cases not autopsied and we know from earlier studies by us and other authors that the cause of death diagnoses were missed in between 30% and 50% of the cases not autopsied.
Conclusion:
The decline in the clinical autopsy rate reduced the value of the death certificate register. An increase in the number of autopsies performed will improve the understanding of disease and cause of death, as well as to better inform next of kin.