Exploring the link between cognitive deficit, self‐esteem, alexithymia, and depressive symptom of schizophrenia

• Published in: Brain and behavior Vol. 12; no. 7; pp. e2648 - n/a
• Main Authors: He, Chen, Zhang, Xueying, Xia, Qingrong, Gao, Hua, Yan, Junwei, Chen, Xuequan, Yuan, Hui, Zhang, Yang, Xie, Wen, Zhu, Cuizhen
• Format: Journal Article
• Language: English
• Published: United States John Wiley & Sons, Inc 01-07-2022; John Wiley and Sons Inc; Wiley
• Subjects: Alexithymia; Brain research; Cognition & reasoning; Cognitive ability; cognitive deficit; depressive symptoms; Disease; Emotions; Memory; Mental disorders; Neuropsychology; Original; Psychiatrists; Psychosis; Schizophrenia; Self esteem; cognitive deficit; self-esteem; alexithymia; schizophrenia; depressive symptoms
• ISSN: 2162-3279; 2162-3279
• DOI: 10.1002/brb3.2648

Objective
To the best of our knowledge, studies have been rarely conducted to assess the correlation between cognitive deficit, self‐esteem, and alexithymia in the depressive symptoms of schizophrenia (SCZ). Therefore, this study aims to explore the risk factors associated with impairment of cognitive function, alexithymia, and self‐esteem among a representative sample of first‐episode schizophrenic patients.
Method
We recruited 107 first‐episode schizophrenic patients (48.6% male, 51.4% female, 36.94 ± 10.73 years) into the research group, according to the Diagnostic and Statistical Manual of Mental Disorders (5th edition). A total of 45 healthy people (51.1% male, 48.9% female, 32.47 ± 10.94 years) were enlisted in the healthy control group. Psychotic symptoms were evaluated using the Positive and Negative Syndrome Scale (PANSS). Cognitive functions were estimated using the Montreal Cognitive Assessment Scale (MoCA). The feelings of respect and self‐acceptance were tested using the Rosenberg Self‐Esteem Scale (RSES). Emotion of identifying and describing were measured by self‐report scale of Toronto Alexithymia Scale‐20 (TAS‐20).
Results
Overall cognitive impairment and alexithymia were found more serious in the patients of SCZ than the healthy group (p < .001, respectively). The patients of SCZ have higher self‐esteem than the healthy group (p = .013). Total score of MoCA, ability of visual space and executive function, and delayed recall were explored had negatively correlation with alexithymia (r = −.319, p = .001; r = −.248, p = .010; r = −0.263, p = .006). Total score of RSES and depressive symptoms of PANSS had a positive correlation with alexithymia (r = .394, p = .001; r = .208, p = .032). Stepwise regression analyses have shown a positive relationship between difficulty describing feelings and depression subscale of PANSS (β = .188, t = −2.007, p = .047) while a negative relationship between externally oriented thinking and depression subscale of PANSS (β = −.244, t = −2.603, p = .011). A positive link correlation also was found between the total scores of TAS and RSES (β = .372, t = 4.144, p = .001). A negative relevance was found between the total scores of TAS and scores of MoCA (β = −.305, t = −3.348, p = .001).
Conclusion
Overall impairment of cognitive function and alexithymia are commonly encountered in SCZ patients. Poor cognitive function, alexithymia, and high level self‐esteem may be specific detective risk factors for the depressive symptoms of SCZ.
This study aims to explore the risk factors associated with impairment of cognitive function, alexithymia, and self‐esteem among a representative sample of first‐episode schizophrenic patients. High self‐esteem and alexithymia are commonly encountered in schizophrenia patients. Poor cognitive function, self‐esteem, and alexithymia may be a specific detective risk factor for the depressive symptoms of SCZ.