Incidence and outcomes of acute kidney injury in octogenarians in Jordan

• Published in: BMC research notes Vol. 11; no. 1; p. 279
• Main Authors: Oweis, Ashraf O, Alshelleh, Sameeha A
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 08-05-2018; BioMed Central; BMC
• Subjects: 80 and over; Acute kidney failure; Acute kidney injury; Age groups; Aged; Aging; Analysis; Angiotensin; Cardiovascular disease; Care and treatment; Congestive heart failure; Contrast agents; Contrast media; Creatinine; Diabetes mellitus; Diagnosis; Geriatrics; Health aspects; Heart failure; Hemodialysis; Hypertension; Incidence; Inflammation; Jordan; Kidney diseases; Kidneys; Medical care; Morbidity; Mortality; Nonsteroidal anti-inflammatory drugs; Octogenarians; Older people; Outcomes; Patient outcomes; Patients; Research Note; Risk factors; Jordan; 80 and over; Aged; Acute kidney injury; Outcomes; Risk factors; Incidence
• ISSN: 1756-0500; 1756-0500
• DOI: 10.1186/s13104-018-3397-3

Improvements in the health care system, resulted in a greater number of geriatric patients diagnosed with acute kidney injury (AKI). We evaluated the incidence and outcome of AKI in octogenarians, as studies in the Middle-East region are few; moreover, treatment approaches, in addition to medical decisions, may require special consideration for advanced age to improve the outcomes.
At King Abdullah II teaching and referral hospital, we recruited patients aged 80-90 years who were admitted to the medical floor between January 2010 and December 2013. Patients were followed-up for at least 1 year after discharge.850 patients were admitted during the study period. Of these, 135 were excluded from our analysis. The most common admission diagnoses were uncontrolled diabetes mellitus and acute coronary syndrome. AKI occurred in 216 patients (30.2%). Using the acute kidney injury network classification; stage 1, stage 2, and stage 3 disease were present in 59, 17.5, and 23.5% of patients, respectively. Of the 115 patients who died before discharge (16.1%), 87 (75.6%) had developed AKI. Hypertension, the use of angiotensin receptor blockers and non-steroidal anti-inflammatory drugs, heart failure, and exposure to radiologic contrast media were significant risk factors for AKI.