The role of low-molecular-weight heparin in recurrent implantation failure: a prospective, quasi-randomized, controlled study

• Published in: Fertility and sterility Vol. 95; no. 8; pp. 2499 - 2502
• Main Authors: Berker, Bülent, M.D, Taşkn, Salih, M.D, Kahraman, Korhan, M.D, Taşkn, Elif Aylin, M.D, Atabekoğlu, Cem, M.D, Sönmezer, Murat, M.D
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 30-06-2011; Elsevier
• Subjects: Adult; Biological and medical sciences; Blood. Blood coagulation. Reticuloendothelial system; Embryo Implantation - drug effects; Embryo Transfer; Enoxaparin - therapeutic use; Female; Gynecology. Andrology. Obstetrics; Humans; implantation; Infertility - therapy; Internal Medicine; low molecular weight heparin; Medical sciences; Obstetrics and Gynecology; Pharmacology. Drug treatments; Pregnancy; pregnancy outcome; Pregnancy Rate; Pregnancy, Multiple; Prospective Studies; Recurrent implantation failure; Reproductive Techniques, Assisted; Sperm Injections, Intracytoplasmic; Treatment Failure; Turkey; Young Adult; Turkey; low molecular weight heparin; implantation; pregnancy outcome; Recurrent implantation failure; Relapse; Prognosis; Gynecology; Low molecular weight heparin; Implantation; Anticoagulant; Obstetrics; Pregnancy; Randomization; Clinical trial; Failure
• ISSN: 0015-0282; 1556-5653
• DOI: 10.1016/j.fertnstert.2010.12.033

Low-molecular-weight heparin did not provide any beneficial effect on pregnancy outcomes in patients with two or more implantation failures. Further trials are needed to confirm a trend in favor of low-molecular-weight heparin in the subgroup with women with three or more implantation failures.