Oral rehydration therapy and Zinc treatment among diarrhoeal children in India: Exploration from latest cross-sectional National Family Health Survey

• Published in: PloS one Vol. 19; no. 10; p. e0307657
• Main Authors: Halli, Shiva S, Biradar, Rajeshwari A, Prasad, Jang B
• Format: Journal Article
• Language: English
• Published: United States Public Library of Science 03-10-2024
• Subjects: Age; Biology and Life Sciences; Birth; Care and treatment; Censuses; Child, Preschool; Children; Children & youth; Complications and side effects; Consumption; Cross-Sectional Studies; Data analysis; Datasets; Diarrhea; Diarrhea - drug therapy; Diarrhea - epidemiology; Diarrhea - therapy; Diarrhea in children; Disadvantaged groups; Economic conditions; Families & family life; Female; Fluid Therapy - methods; Frame design; Health; Health aspects; Health services; Health Surveys; Hospitals; Households; Humans; India - epidemiology; Infant; Infant, Newborn; International organizations; Logistics; Male; Medicine and Health Sciences; Mothers; Oral rehydration therapy; Patient outcomes; People and Places; Polls & surveys; Random sampling; Regression analysis; Rehydration; Rural areas; Sampling designs; Socioeconomic factors; Statistical analysis; Statistical sampling; Supply chains; Surveys; Variables; Zinc; Zinc - therapeutic use; Zinc in the body; India
• ISSN: 1932-6203; 1932-6203
• DOI: 10.1371/journal.pone.0307657

Diarrhoea is one of the deadliest diseases and causing death among children in India, but no systematic attempt is made to understand it especially its control using oral rehydration salts (ORS). It is well known that use of ORS and Zinc have been effective in containing diarrhoea among children. An attempt is made using large scale national data set in India to understand use of ORS and Zinc to control diarrhoea and their associated factors among diarrhoeal children under five in India.
Publicly available most recent cross-sectional National Family Health Survey data in India was used for the study. The multi-stage cluster sampling design was used with 2011 Census of India as a sampling frame. Households were selected using a Systematic Random Sampling design from selected primary sampling units in rural and urban clusters. From the selected households, the eligible children were those who suffered from diarrhoea in the two weeks preceding the survey and were less than 5 years old. Using this criterion, out of 232,920 children in the survey of less than five years, 16,213 sample diarrheal children found to be available for the study. Both descriptive and inferential statistical techniques were used to analyse the data.
Across India, 61% and 31% of the children were given ORS and Zinc respectively. However, combined ORS + Zinc treatment was only around 24%. The treatment of ORS, Zinc, and combined ORS + Zinc supplementations were significantly higher among younger children, children of 24-35 age group mothers, children from rich wealth index groups, belong to Hindu religion and general caste compared to their counterparts. The logistic regression results showed that consumption of ORS among diarrhoeal children under five years of age depends upon size of a child at birth. For instance, diarrheal children who were very small size at birth compared to very large at birth, had 39% lower odds of consuming ORS (AOR = 0.61; CI 0.48, 0.78; p<0.001). Another important variable is place of first treatment sought for diarrheal children. That is children who first sought treatment in private hospital compared to government hospital had 52% lower odds of ORS consumption. The logistic regression adjusted AORs are similar with Zinc and ORS + Zinc supplementations.
To improve the coverage and management of childhood diarrhoea in India, planning activities should focus not only on distribution, and increasing knowledge of ORS preparation especially for urban slum residents and rural disadvantaged groups through demonstration. There should be also proper focus on providing ongoing pathways to ensure proper supply chains.