Lessons from a standardized program using PET–CT to avoid neck dissection after primary radiotherapy for N2 squamous cell carcinoma of the oropharynx

Highlights • This is one of the few prospective studies of using a 12-week PET–CT to determine the need for neck dissection. • We limit our study to N2 disease where the question is most relevant. • We demonstrate late recurrences after an interval of negative imaging.

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Bibliographic Details
Published in:	Oral oncology Vol. 51; no. 9; pp. 870 - 874
Main Authors:	Hitchcock, Kathryn E, Amdur, Robert J, Mendenhall, William M, Werning, John W, Drane, Walter E, Mancuso, Anthony A
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 01-09-2015
Subjects:	Adult Aged Aged, 80 and over Carcinoma, Squamous Cell - diagnostic imaging Carcinoma, Squamous Cell - radiotherapy Female Hematology, Oncology and Palliative Medicine Humans Male Middle Aged Neck dissection Neck Dissection - methods Neoplasm Recurrence, Local - prevention & control Oropharyngeal Neoplasms - diagnostic imaging Oropharyngeal Neoplasms - radiotherapy Oropharynx Otolaryngology PET Positron-Emission Tomography - methods Prognosis Prospective Studies Radiation therapy Radiochemotherapy Sensitivity and Specificity Tomography, X-Ray Computed - methods Oropharynx Radiation therapy Neck dissection PET Radiochemotherapy
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Summary:	Highlights • This is one of the few prospective studies of using a 12-week PET–CT to determine the need for neck dissection. • We limit our study to N2 disease where the question is most relevant. • We demonstrate late recurrences after an interval of negative imaging.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	1368-8375 1879-0593
DOI:	10.1016/j.oraloncology.2015.06.012