Psoriasis and increased prevalence of hypertension and diabetes mellitus

• Published in: Indian journal of dermatology Vol. 56; no. 5; pp. 533 - 536
• Main Authors: Ghiasi, Maryam, Nouri, Mohammad, Abbasi, Ata, Hatami, Parvaneh, Abbasi, Mohammad Amin, Nourijelyani, Keramat
• Format: Journal Article
• Language: English
• Published: India Medknow Publications and Media Pvt. Ltd 01-09-2011; Medknow Publications & Media Pvt. Ltd; Medknow Publications & Media Pvt Ltd; Wolters Kluwer Medknow Publications
• Subjects: Demographic aspects; Diabetes; Diabetes mellitus; Distribution; Hypertension; Original; Psoriasis; Risk factors; Iran; hypertension; Diabetes mellitus; psoriasis
• ISSN: 0019-5154; 1998-3611
• DOI: 10.4103/0019-5154.87149

Psoriasis is an autoimmune skin disease and associated with other diseases such as cardiovascular, hypertension, and diabetes mellitus.
Our aim was to explore the prevalence of diabetes mellitus and hypertension in psoriatic patients.
Between April 2008 and May 2010, a total of 304 psoriatic and 300 nonpsoriatic patients were enrolled in this cross sectional study. Data were obtained on age, sex, weight, heights, etc; documented medical history of diabetes mellitus and hypertension; family history of diabetes mellitus and hypertension in first relatives, history of smoking.
There was no significant difference in age and gender distribution between two groups. There was also no difference in body mass index between two groups. Within psoriatic group, 79.3% of patients present with plaque type of the disease and 20.7% present with other types. The results showed that within psoriatic patients, the prevalence of diabetes in women is significantly higher than in men (OR=1.93, CI95%: 1.1-3.6, P=0.004) but this difference is not present in nonpsoriatic patients. The results also showed that the prevalence of diabetes in psoriatic patients is significantly higher than nonpsoriatic patients (OR=1.76, CI95%: 1.11-2.8, P=0.015). The data showed that psoriatic patients were more likely to develop hypertension compared with nonpsoriatic patients (OR=2.2, CI95%: 1.2-4.6, P=0.003). According to results, although smoking rate within psoriatic patients is higher than the other group but the difference was not significant.
Psoriatic patients have an increased risk of developing metabolic syndrome and hypertension in comparison to nonpsoriatic patients.