Therapeutic plasma exchange an emerging treatment modality: A 3-year retrospective analysis of patients admitted in a multispecialty hospital of North India

• Published in: Asian journal of transfusion science Vol. 15; no. 1; pp. 46 - 51
• Main Authors: Solanki, Archana, Singh, Ashutosh, Chauhan, Abhishek, Agarwal, Devisha, Himanshu, D, Chandra, Tulika
• Format: Journal Article
• Language: English
• Published: India Wolters Kluwer India Pvt. Ltd 01-01-2021; Medknow Publications and Media Pvt. Ltd; Medknow Publications & Media Pvt. Ltd; Wolters Kluwer - Medknow; Wolters Kluwer Medknow Publications
• Subjects: american society of apheresis; Analysis; Antibodies; Apheresis; Blood; Blood transfusions; citrate anticoagulation; extracorporeal; Health aspects; Medical technology; Original; Plasma; Plasma exchange (Therapeutics); therapeutic plasma exchange; Trends; India; therapeutic plasma exchange; extracorporeal; American society of apheresis; citrate anticoagulation
• ISSN: 0973-6247; 1998-3565
• DOI: 10.4103/ajts.ajts_125_20

Background and Aims: Therapeutic plasma exchange (TPE) is increasingly used throughout the medical field. We aimed to analyze the various aspects of TPE practices at our hospital in terms of clinical indications, technical feasibility, safety, outcome as well as complications associated with the procedures.
Materials and Methods: The data included demographic profiles, clinical parameters, and technical characteristics of each TPE procedure. All the information was noted in data spread sheet (Microsoft Excel 2013) for further analysis.
Results: This is a 3-year retrospective study of total 266 TPE procedures carried out on 92 patients with different clinical conditions. Out of them, 55 (59.8%) were male and 37 (40.2%) were female patients. There were six major categories such as (1) neurological, (2) hematological, (3) gastrological, (4) renal, (5) rheumatic, and (6) others. The TPE treatment was highest in neurology group (60.2%), followed by gastrology group (24.4%). Most of the procedures (82.6%) were according to the American society of apheresis 2016 I or II categories (76/92 patients).
Conclusion: TPE is beneficial and used as primary or secondary adjunctive therapy for a wide spectrum of various diseases and syndromes. TPE is considered as safe, cost-effective, and life-saving treatment modality in various diseases.