A Rare Masquerader of Lung Cancer: Nonsecretory Multiple Myeloma with Plasmacytoma of Bone Presenting as Acute Kidney Injury

• Published in: Internal Medicine Vol. 49; no. 19; pp. 2133 - 2135
• Main Authors: Guney, Ibrahim, Solak, Yalcin, Atalay, Huseyin, Altintepe, Lutfullah, Tonbul, H. Zeki
• Format: Journal Article
• Language: English
• Published: Japan The Japanese Society of Internal Medicine 01-01-2010
• Subjects: acute kidney injury; Acute Kidney Injury - etiology; Adult; Bone cancer; Bone marrow; Bone mass; Bone Neoplasms - complications; Bone Neoplasms - diagnosis; Bone Neoplasms - diagnostic imaging; Cell lineage; Cell proliferation; Chest; Diagnosis, Differential; Humans; Hypercalcemia; Injuries; Ionizing radiation; Kidney; Lung cancer; Lung Neoplasms - diagnosis; Lymphocytes B; Male; masquerader; Multiple myeloma; Multiple Myeloma - complications; Multiple Myeloma - diagnosis; Multiple Myeloma - diagnostic imaging; nonsecretory multiple myeloma; Plasma cells; Plasmacytoma; Plasmacytoma - complications; Plasmacytoma - diagnosis; Plasmacytoma - diagnostic imaging; plasmacytoma of bone; Radiography; Urine
• ISSN: 0918-2918; 1349-7235; 1349-7235
• DOI: 10.2169/internalmedicine.49.3709

Multiple myeloma (MM) is a neoplasm of B cell lineage characterized by excessive proliferation of abnormal plasma cells which produce immunglobulins. If a monoclonal spike is not found in serum or urine but the patient has clinical findings and bone marrow plasma cell infiltration suggestive of MM, then the patient may have a rare subtype known as nonsecretory multiple myeloma (NSMM). Here, we describe a rare case of NSMM with plasmacytoma of bone who presented with severe hypercalcemia, acute kidney injury and a large thoracal mass on chest X-ray masquerading as lung cancer.