The anti-inflammatory effect of the platelet-rich plasma in the periodontal pocket

• Published in: European journal of dentistry Vol. 12; no. 4; pp. 528 - 531
• Main Authors: Abdul Ameer, Lubaba A., Raheem, Zainab J., Abdulrazaq, Saif Saadedeen, Ali, Basima Gh, Nasser, Maysaa Mahdi, Khairi, Azza Wala Aldeen
• Format: Journal Article
• Language: English
• Published: A-12, Second Floor, Sector -2, NOIDA -201301, India Thieme Medical and Scientific Publishers Private Ltd 01-10-2018; Wolters Kluwer India Pvt. Ltd; Medknow Publications and Media Pvt. Ltd; Medknow Publications & Media Pvt Ltd
• Subjects: Analysis; Blood cell count; Care and treatment; Original; Original Article; Periodontal disease; Platelet-rich plasma therapy; Risk factors; Treatment outcome; Lymphocyte count; platelet-rich plasma; periodontal pocket
• ISSN: 1305-7456; 1305-7464
• DOI: 10.4103/ejd.ejd_49_18

ABSTRACT
Objective
: Chronic periodontitis (CP) is a common inflammatory disease that causes destruction to the supporting tissues of the teeth. Many treatment modalities tried to stop the disease progression. Platelet-rich plasma (PRP) is one of the regenerative methods that used in adjunct to conventional periodontal treatment. The aim of this study was to evaluate the anti-inflammatory effect of PRP by monitoring the lymphocyte count before and after its application to the periodontal pocket.
Materials and Methods
: Twenty patients, with CP and a pocket depth equal to or deeper than 4 mm, subjected to scaling, root planing, and PRP injection into the pocket. The lymphocyte count measured before and after 1 month from PRP application. Clinical periodontal parameters were taken during two visits (1 month apart), with customized stent fabrication.
Results
: All clinical periodontal parameters showed a reduction in their value following 1 month of PRP application. . There was a noticeable reduction in lymphocyte count from (mean 2.47 ± 0.91) to (mean 1.94 ± 0.77).
Conclusion
: In addition to its traditional uses, PRP has a great role in the periodontal treatment by its anti-inflammatory effect.