Diffusion-weighted imaging of kainic acid lesions in the rat brain

We present T2-weighted and diffusion-weighted images of kainic acid lesions in the rat brain. Our observations show improved image contrast between edematous lesions and unaffected tissue using diffusion-weighted imaging. Furthermore, we show that the anisotropic intensity changes associated with th...

Full description

Saved in:

Bibliographic Details
Published in:	Magnetic resonance in medicine Vol. 20; no. 1; p. 158
Main Authors:	King, M D, van Bruggen, N, Ahier, R G, Cremer, J E, Hajnal, J V, Williams, S R, Doran, M
Format:	Journal Article
Language:	English
Published:	United States 01-07-1991
Subjects:	Amygdala - drug effects Amygdala - pathology Animals Brain - drug effects Brain - pathology Corpus Callosum - drug effects Corpus Callosum - pathology Corpus Striatum - drug effects Corpus Striatum - pathology Diffusion Kainic Acid - adverse effects Magnetic Resonance Spectroscopy Male Nerve Degeneration Putamen - drug effects Putamen - pathology Rats Rats, Inbred Strains
Online Access:	Get more information
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	We present T2-weighted and diffusion-weighted images of kainic acid lesions in the rat brain. Our observations show improved image contrast between edematous lesions and unaffected tissue using diffusion-weighted imaging. Furthermore, we show that the anisotropic intensity changes associated with this sequence can be used to highlight white matter tracts and to provide information concerning their orientation in the rat brain.
ISSN:	0740-3194
DOI:	10.1002/mrm.1910200117