Low-Density Lipoprotein Receptor–Related Protein-1 Is a Therapeutic Target in Acute Myocardial Infarction

• Published in: JACC. Basic to translational science Vol. 2; no. 5; pp. 561 - 574
• Main Authors: Toldo, Stefano, PhD, Austin, Dana, MS, Mauro, Adolfo G., MS, Mezzaroma, Eleonora, PhD, Van Tassell, Benjamin W., PharmD, Marchetti, Carlo, PhD, Carbone, Salvatore, MS, Mogelsvang, Soren, PhD, Gelber, Cohava, PhD, Abbate, Antonio, MD, PhD
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01-10-2017; Elsevier
• Subjects: Cardiovascular; ischemia reperfusion; low-density lipoprotein receptor-related protein-1; PRECLINICAL RESEARCH; serine protease inhibitor; SERPINs; alpha-1 antitrypsin; low-density lipoprotein receptor-related protein-1; LRP1; HRP; ischemia reperfusion; left ventricular fractional shortening; antithrombin III; LV; phosphate-buffered saline; LPS; SERPINs; intravenous; TUNEL; horseradish peroxidase; low-density lipoprotein receptor–related protein-1; left ventricular; interleukin; AMI; PBS; SERPIN; serine protease inhibitor; IL; TBS; AT III; alpha-2 macroglobulin; terminal deoxynucleotidyl transferase dUTP nick end labeling; IV; SEC; AAT; LVFS; A2MG; serine protease inhibitor–enzyme complex; tris-buffered saline; lipopolysaccharide; acute myocardial infarction; ATIII; A2MG, alpha-2 macroglobulin; ATIII, antithrombin III; TBS, tris-buffered saline; AMI, acute myocardial infarction; IV, intravenous; LVFS, left ventricular fractional shortening; LV, left ventricular; SERPIN, serine protease inhibitor; LRP1, low-density lipoprotein receptor–related protein-1; HRP, horseradish peroxidase; PBS, phosphate-buffered saline; IL, interleukin; LPS, lipopolysaccharide; SEC, serine protease inhibitor–enzyme complex; AAT, alpha-1 antitrypsin; TUNEL, terminal deoxynucleotidyl transferase dUTP nick end labeling
• ISSN: 2452-302X; 2452-302X
• DOI: 10.1016/j.jacbts.2017.05.007

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