Association between traditional cholesterol parameters, lipoprotein particle concentration, novel biomarkers and carotid plaques in retired National Football League players

• Published in: Atherosclerosis Vol. 222; no. 2; pp. 551 - 556
• Main Authors: Virani, Salim S, Pompeii, Lisa, Lincoln, Andrew E, Dunn, Reginald E, Tucker, Andrew M, Nambi, Vijay, Nasir, Khurram, Vogel, Robert A, Boone, Jeffrey L, Roberts, Arthur J, Ballantyne, Christie M
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier Ireland Ltd 01-06-2012; Elsevier
• Subjects: Adult; Aged; Asymptomatic Diseases; atherosclerosis; Atherosclerosis (general aspects, experimental research); Biological and medical sciences; Biomarkers; Biomarkers - blood; Blood and lymphatic vessels; C-reactive protein; C-Reactive Protein - analysis; Cardiology. Vascular system; Cardiovascular; carotid arteries; Carotid Arteries - diagnostic imaging; Carotid Arteries - pathology; Carotid Artery Diseases - blood; Carotid Artery Diseases - diagnosis; Carotid Artery Diseases - diagnostic imaging; Carotid Artery Diseases - epidemiology; Carotid Artery Diseases - pathology; Cholesterol; Cholesterol - blood; Cholesterol, LDL - blood; confidence interval; Cross-Sectional Studies; Football; Fundamental and applied biological sciences. Psychology; General aspects; Humans; Lipoproteins; Lipoproteins, LDL - blood; Logistic Models; low density lipoprotein; Male; Medical sciences; metabolic syndrome; Metabolic Syndrome - blood; Metabolic Syndrome - epidemiology; Middle Aged; Odds Ratio; Plaque, Atherosclerotic; Predictive Value of Tests; Prevalence; regression analysis; Retired NFL players; Retirement; Risk Assessment; Risk Factors; screening; Subclinical atherosclerosis; Ultrasonography, Doppler; United States - epidemiology; Vertebrates: cardiovascular system; Biomarkers; Lipoproteins; Retired NFL players; Subclinical atherosclerosis; Cholesterol; Lipids; Cardiovascular disease; Asymptomatic; Lipoprotein; Artery; Vascular disease; Particle; Blood vessel; Carotid; Atherosclerosis; Circulatory system
• ISSN: 0021-9150; 1879-1484
• DOI: 10.1016/j.atherosclerosis.2012.03.031

Highlights ► We assessed the association between lipid parameters and carotid plaques in retired NFL players. ► Carotid artery plaques were common and seen in 41% of retired NFL players. ► Plaques were more strongly associated with LDL particle concentration than LDL cholesterol.