Individual differences in trait anxiety are associated with white matter tract integrity in the left temporal lobe in healthy males but not females

• Published in: Neuroscience Vol. 217; pp. 77 - 83
• Main Authors: Montag, C, Reuter, M, Weber, B, Markett, S, Schoene-Bake, J.-C
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier Ltd 16-08-2012; Elsevier
• Subjects: Adolescent; Adult; Anisotropy; Anxiety; Anxiety - pathology; Behavioral Inhibition System; Biological and medical sciences; Brain Mapping; Computed tomography; Data processing; Depression; Diffusion Tensor Imaging; Female; Functional magnetic resonance imaging; Fundamental and applied biological sciences. Psychology; Harm avoidance; Hemispheric laterality; Humans; Image Processing, Computer-Assisted; Individuality; Male; Middle Aged; Nerve Fibers, Myelinated - pathology; Nervous system; Neurology; Neuroticism; Personality; Sex Characteristics; Sex differences; Substantia alba; Temporal lobe; Temporal Lobe - pathology; Vertebrates: nervous system and sense organs; Neuroticism; ILF; SLF; inferior fronto-occipital fasciculus; uncinate fasciculus; Eysenck’s Personality Inventory; UF; personality; IFOF; posterior cingulate gyrus; Temperament and Character Inventory; Behavioral Activation System; Harm avoidance; Behavioral Inhibition System; superior longitudinal fasciculus; BIS; PCA; fMRI; BAS; PCG; DTI; diffusion tensor imaging; fractional anisotropy; EPQ-R; FA; FLIRT; FMRIB Linear Image Registration Tool; TCI; inferior longitudinal fasciculus; functional magnetic resonance imaging; principal component analysis; Temporal lobe; Female; Male; Anxiety; Behavior; White matter; Avoidance; Diffusion tensor imaging
• ISSN: 0306-4522; 1873-7544
• DOI: 10.1016/j.neuroscience.2012.05.017

Highlights ► The present study investigates trait anxiety by means of DTI. ► The study links white matter integrity of the temporal lobe to trait anxiety in humans. ► The association between FA values and anxiety can be observed in males only.