Frequency domains of resting state default mode network activity in schizophrenia

• Published in: Psychiatry research. Neuroimaging Vol. 214; no. 1; pp. 80 - 82
• Main Authors: Mingoia, Gianluca, Langbein, Kerstin, Dietzek, Maren, Wagner, Gerd, Smesny, Stefan, Scherpiet, Sigrid, Maitra, Raka, Reichenbach, Jürgen R, Schlösser, Ralf G.M, Gaser, Christian, Sauer, Heinrich, Nenadic, Igor
• Format: Journal Article
• Language: English
• Published: Shannon Elsevier Ireland Ltd 30-10-2013; Elsevier
• Subjects: Adult; Adult and adolescent clinical studies; Biological and medical sciences; Brain - physiopathology; Cerebral Cortex; Cortex; Default mode network (DMN); Female; Functional Neuroimaging; Humans; Magnetic Resonance Imaging; Male; Medical sciences; Middle Aged; Nerve Net - physiopathology; Power spectrum analysis; Probabilistic independent component analysis (pICA); Psychiatry; Psychology. Psychoanalysis. Psychiatry; Psychopathology. Psychiatry; Psychoses; Radiology; Resting state; Schizophrenia; Schizophrenia - physiopathology; Probabilistic independent component analysis (pICA); Schizophrenia; Default mode network (DMN); Resting state; Power spectrum analysis; Cortex; Human; Default mode network; Central nervous system; Activity; Eating disorder; Encephalon; Psychosis; Pica; Rest
• ISSN: 0925-4927; 1872-7506
• DOI: 10.1016/j.pscychresns.2013.05.013

Abstract Probabilistic independent component analysis was applied to identify the default mode network (DMN) in resting state data obtained with functional magnetic resonance imaging from 25 DSM-IV schizophrenia and 25 matched healthy subjects. Power spectrum analysis showed a significant diagnosis×frequency interaction and higher power in one frequency band, indicating an alteration of DMN frequency spectrum in schizophrenia.