Phytochemistry and Biological Activities of Amburana cearensis (Allemão) ACSm

• Published in: Molecules (Basel, Switzerland) Vol. 27; no. 2; p. 505
• Main Authors: Silveira, Zildene de Sousa, Macêdo, Nair Silva, Bezerra, Suieny Rodrigues, Siyadatpanah, Abolghasem, Coutinho, Henrique Douglas Melo, Seifi, Zahra, Kim, Bonglee, da Cunha, Francisco Assis Bezerra, Balbino, Valdir de Queiroz
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 14-01-2022; MDPI
• Subjects: Amburana cearensis; Anti-Infective Agents - pharmacology; Anti-Inflammatory Agents; Antiinfectives and antibacterials; Antioxidants; Antioxidants - pharmacology; Asthma; Bronchitis; Chemical composition; Constituents; coumarins; Ethnopharmacology; Fabaceae - chemistry; Fatty acids; Flavonoids; Glucosides - pharmacology; Glycosides; High performance liquid chromatography; Inflammation; Influenza; Liquid chromatography; Literature reviews; Medicine; Minority & ethnic groups; Neuroprotection; Pain; Pain perception; pharmacology; Phenolic acids; Phenols; Phytochemicals; Phytochemicals - pharmacology; phytochemistry; Phytotherapy; Plant Extracts - pharmacology; Respiratory system; Review; Seeds; Sinusitis; Toxicity; Triterpenoids; Tropical diseases; Brazil; Bolivia; Amburana cearensis; coumarins; ethnopharmacology; pharmacology; phytochemistry
• ISSN: 1420-3049; 1420-3049
• DOI: 10.3390/molecules27020505

(Allemão) ACSm. belongs to the Fabaceae family and occurs in the Brazilian semiarid, Argentina, Paraguay, Bolivia, and Peru. Numerous studies that portray its ethnobotany, use in popular medicine, chemical composition, and biological activities exist in the literature. This review aimed to provide an overview of the chemical composition, ethnopharmacology, and biological activities associated with
and its isolated constituents. Information was collected from internet searches in the Scopus, Medline, PubMed, Google Scholar, and ScienceDirect databases were performed covering publications from 1997-2020. An ethnopharmacological literature analysis revealed that
is used to treat a wide range of respiratory disorders in addition to intestinal, circulatory, and inflammatory problems. Coumarins, flavonoids, phenolic glycosides, phenolic acids, phenylpropanoid derivatives, and triterpenoids, among others, have been reported as active compounds, with High-Performance Liquid Chromatography (HPLC) being the main analytical technique used. The
extracts and compounds presented several biological activities, including antimicrobial, antinociceptive, anti-inflammatory, antioxidant, neuroprotective, and myorelaxant activities, among others. This review provides a useful bibliography for future investigations and
applications; however, future studies should focus on its toxic effects and the mechanisms of action of its extracts and isolated constituents to guide clinical applications.