Maternal and fetal exposure to bisphenol A in Korea

• Published in: Reproductive toxicology (Elmsford, N.Y.) Vol. 25; no. 4; pp. 413 - 419
• Main Authors: Lee, Young Joo, Ryu, Heui-Young, Kim, Hyun-Kyung, Min, Chung Sik, Lee, Jin Hee, Kim, Eunhee, Nam, Bong Hyun, Park, Joo Hong, Jung, Jin Young, Jang, Dong Deuk, Park, Eun Young, Lee, Kwan-Hee, Ma, Jin-Young, Won, Hey-Sung, Im, Moon-Whan, Leem, Jong-Han, Hong, Yun-Chul, Yoon, Hae-Seong
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01-08-2008; Elsevier
• Subjects: Adult; Benzhydryl Compounds; Biological and medical sciences; Biomonitoring; Bisphenol A; Embryology: invertebrates and vertebrates. Teratology; Endocrine Disruptors - blood; Environmental Monitoring; Estrogens, Non-Steroidal - blood; Female; Fetal Blood - chemistry; Fetus; Fundamental and applied biological sciences. Psychology; Human exposure; Humans; Korea; Maternal Exposure; Maternal serum; Maternal-Fetal Exchange; Medical sciences; Phenols - blood; Pregnancy; Pregnant woman; Teratology. Teratogens; Toxicology; Umbilical cord blood; Asia; Korea; Korea, Rep; Bisphenol A; Pregnant woman; Biomonitoring; Umbilical cord blood; Maternal serum; Human exposure; Fetus; Korea; Exposure; Mother; Bisphenol A;Human exposure;Biomonitoring;Pregnant woman;Maternal serum;Fetus;Umbilical cord blood;Korea
• ISSN: 0890-6238; 1873-1708
• DOI: 10.1016/j.reprotox.2008.05.058

Bisphenol A (BPA) is a well-known endocrine disrupter used widely. Despite the potential risk of human exposure to BPA, little information exists concerning maternal and fetal exposure to BPA during pregnancy in Korea. This study purposed to evaluate the correlation between maternal and fetal exposure, and to determine exposure levels to BPA in Korean pregnant women and their fetuses. Maternal blood and umbilical cord blood were collected from 300 subjects, and total BPA levels were measured. Blood BPA concentrations ranged from non-detectable to 66.48
μg/L in pregnant women and from non-detectable to 8.86
μg/L in umbilical cords. Serum BPA levels in most pregnant women were higher than in corresponding fetal umbilical cords and a positive correlation was found between in maternal and fetal BPA concentrations (
p
<
0.05).