Results of Kidney Transplantation From Deceased Donors With Acute Kidney Injury

• Published in: Transplantation proceedings Vol. 47; no. 1; pp. 42 - 44
• Main Authors: Molina, M, Apaza, J, González Monte, E, Gutiérrez Martínez, E, Sevillano, A.M, Marín, J.P, Polanco, N, Hernández, A, Praga, M, Andrés, A
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 2015
• Subjects: Acute Kidney Injury; Adult; Aged; Cadaver; Creatinine - blood; Delayed Graft Function - diagnosis; Delayed Graft Function - epidemiology; Delayed Graft Function - physiopathology; Female; Graft Survival; Humans; Incidence; Kidney - physiopathology; Kidney Failure, Chronic - mortality; Kidney Failure, Chronic - physiopathology; Kidney Failure, Chronic - surgery; Kidney Transplantation; Male; Middle Aged; Retrospective Studies; Surgery; Tissue and Organ Procurement; Treatment Outcome
• ISSN: 0041-1345; 1873-2623
• DOI: 10.1016/j.transproceed.2014.11.007

Abstract Background Different strategies have been initiated to shorten the waiting list time to receive a kidney transplant. Donors with acute kidney injury (AKI) may be a new option. Methods Fifty-nine patients received a kidney transplant from an AKI donor defined as having serum creatinine >2 mg/dL at the time of organ procurement. They were compared with a transplant group with normal kidney function defined as creatinine <1.5 mg/dL organ procurement in the same time period, paired by donor and recipient age (control group). Initial evolution, at 1 year, and at the end of the follow-up were evaluated. Results The AKI donor group had greater delayed graft function (68% versus 36%, P  < .01). Graft and recipient survival were similar in both groups at 1 year (92% versus 88%, P  = NS; 97% versus 98%, P  = NS) and at the end of follow-up (66% versus 66%, P  = NS; 90% versus 88%, P  = NS). Serum creatinine at 1 year and at the end of the follow-up did not show any differences (1.4 ± 0.5 versus 1.4 ± 0.7 mg/dL, P  = NS; 1.4 ± 0.5 versus 1.6 ± 0.9 mg/dL, P  = NS). Conclusions The transplants from donors with AKI showed greater incidence of delayed graft function, but this did not affect the short- or long-term prognosis of the graft or recipient. This type of donor may be a source of acceptable kidneys.