Intravenous thrombolysis for acute ischemic stroke: From alteplase to tenecteplase

Stroke is one of the primary causes of morbidity and death worldwide. While intravenous (IV) thrombolysis with alteplase has been widely proven to be beneficial for acute ischemic stroke patients, it still has many limitations. Tenecteplase, a revised version of alteplase, is a potential alternative...

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Bibliographic Details
Published in:	Brain circulation Vol. 9; no. 2; pp. 61 - 63
Main Authors:	Yang, Nan, Lee, Hangil, Wu, Chuanjie
Format:	Journal Article
Language:	English
Published:	India Wolters Kluwer India Pvt. Ltd 01-04-2023 Medknow Publications and Media Pvt. Ltd Medknow Publications & Media Pvt. Ltd Wolters Kluwer - Medknow
Subjects:	Ischemia Stroke (Disease) Tenecteplase stroke tenecteplase Alteplase
Online Access:	Get full text
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Summary:	Stroke is one of the primary causes of morbidity and death worldwide. While intravenous (IV) thrombolysis with alteplase has been widely proven to be beneficial for acute ischemic stroke patients, it still has many limitations. Tenecteplase, a revised version of alteplase, is a potential alternative IV thrombolytic agent that has benefits over alteplase. The aim of this mini-review is to summarize the advancements in IV thrombolysis for severe ischemic stroke, specifically the development and transition from alteplase to tenecteplase.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	2394-8108 2455-4626
DOI:	10.4103/bc.bc_70_22