The mean platelet volume in patients with obesity

The mean platelet volume in patients with obesity

Mean platelet volume (MPV), a determinant of platelet function, is a newly emerging risk factor for atherothrombosis. The present study was designed to evaluate MPV in patients with obesity compared with non-obese control subjects. We selected 100 non-obese subjects and 100 subjects with obesity [bo...

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Bibliographic Details
Published in:International journal of clinical practice (Esher) Vol. 59; no. 8; p. 981
Main Authors: Coban, E, Ozdogan, M, Yazicioglu, G, Akcit, F
Format: Journal Article
Language:English
Published: England 01-08-2005
Subjects:
Adult
Blood Platelets - pathology
Body Mass Index
Case-Control Studies
Female
Humans
Male
Middle Aged
Obesity - blood
Platelet Activation
Platelet Count
Risk Factors
Thromboembolism - blood
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Summary:Mean platelet volume (MPV), a determinant of platelet function, is a newly emerging risk factor for atherothrombosis. The present study was designed to evaluate MPV in patients with obesity compared with non-obese control subjects. We selected 100 non-obese subjects and 100 subjects with obesity [body mass index (BMI) > or =30 kg/m(2)] matched for age and gender. The MPV was significantly higher in obese group than in non-obese control group (10.3 +/- 1.2 vs. 9.0 +/- 0.8 fl, p < 0.01). MPV was positively correlated with BMI in obese group (p < 0.05). Increased MPV may be a possible cause for increased cardiovascular risk in patients with obesity.
ISSN:1368-5031
DOI:10.1111/j.1742-1241.2005.00500.x