Osteoarticular complications related to HIV infection and highly active antiretroviral therapy

• Published in: The Brazilian journal of infectious diseases Vol. 11; no. 4; pp. 426 - 429
• Main Authors: Lima, Ana Lúcia Lei Munhoz, Zumiotti, Arnaldo Valdir, Camanho, Gilberto Luis, Benegas, Eduardo, dos Santos, Alexandre Leme Godoy, D'Elia, Caio Oliveira, Oliveira, Priscila Rosalba Domingos
• Format: Journal Article
• Language: English
• Published: Brazil Brazilian Society of Infectious Diseases 01-08-2007; Elsevier
• Subjects: acquired immunodeficiency syndrome; Anti-HIV Agents - adverse effects; Anti-HIV Agents - therapeutic use; antiretroviral agents; Antiretroviral Therapy, Highly Active - adverse effects; Bone Diseases - chemically induced; Bone Diseases - diagnosis; Bone Diseases - therapy; Carpal Tunnel Syndrome - chemically induced; Carpal Tunnel Syndrome - diagnosis; Carpal Tunnel Syndrome - therapy; HIV; HIV Infections - drug therapy; Humans; INFECTIOUS DISEASES; Joint Diseases - chemically induced; Joint Diseases - diagnosis; Joint Diseases - therapy; osteoarticular; antiretroviral agents; HIV; osteoarticular; acquired immunodeficiency syndrome
• ISSN: 1413-8670; 1678-4391; 1413-8670
• DOI: 10.1590/S1413-86702007000400012

With the significant increase in life expectancy for HIV-infected patients in the era of high potency antiretroviral therapy, major metabolic changes have been observed due to the prolonged period of the viral infection and the treatment itself. Osteoarticular changes resulting from these processes are mainly reported in long term HIV-infected patients receiving high potency antiretroviral therapy and include osteopenia/osteoporosis, osteonecrosis, carpal tunnel syndrome and adhesive capsulitis of the shoulder.