Regional Specificity in the Drosophila Midgut: Setting Boundaries with Stem Cells

Many organs consist of distinct subregions with specialized physiological roles, but how regional boundaries are upheld during cellular renewal is largely unknown. Recently, Buchon et al. (2013) and Marianes and Spradling (2013) showed that subregions of the Drosophila midgut are maintained by patte...

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Bibliographic Details
Published in:	Cell stem cell Vol. 13; no. 4; pp. 375 - 376
Main Author:	O’Brien, Lucy Erin
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 03-10-2013
Subjects:	Animals Drosophila Drosophila - anatomy & histology Intestines - anatomy & histology
Online Access:	Get full text
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Summary:	Many organs consist of distinct subregions with specialized physiological roles, but how regional boundaries are upheld during cellular renewal is largely unknown. Recently, Buchon et al. (2013) and Marianes and Spradling (2013) showed that subregions of the Drosophila midgut are maintained by patterned transcription factors and compartmentalized stem cell progeny.
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Commentary-1 ObjectType-Article-1 ObjectType-Feature-2
ISSN:	1934-5909 1875-9777
DOI:	10.1016/j.stem.2013.09.008