The Identification and Clinical Applications of Mutated Antigens in the Era of Immunotherapy

The era of personalized cancer therapy is here. Advances in the field of immunotherapy have paved the way for the development of individualized neoantigen-based therapies that can translate into favorable treatment outcomes and fewer side effects for patients. Addressing challenges related to the id...

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Bibliographic Details
Published in:	Cancers Vol. 14; no. 17; p. 4255
Main Authors:	Kye, Yae, Nagineni, Lokesh, Gadad, Shrikanth, Ramirez, Fabiola, Riva, Hannah, Fernandez, Lorena, Samaniego, Michelle, Holland, Nathan, Yeh, Rose, Takigawa, Kei, Dhandayuthapani, Subramanian, Chacon, Jessica
Format:	Journal Article
Language:	English
Published:	Switzerland MDPI AG 31-08-2022 MDPI
Subjects:	Antigens Apoptosis Breast cancer By products Cancer Cancer therapies Cytotoxicity Genomes Health aspects Identification and classification Immune system Immunotherapy Ligands Lymphocytes Melanoma Metastasis Methods Monoclonal antibodies Mutation Neoantigens Ovarian cancer Patients Peptides Proteins Review Success Tumors United States neoantigen tumor-associated antigens mutated antigen immunotherapy
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Summary:	The era of personalized cancer therapy is here. Advances in the field of immunotherapy have paved the way for the development of individualized neoantigen-based therapies that can translate into favorable treatment outcomes and fewer side effects for patients. Addressing challenges related to the identification, access, and clinical application of neoantigens is critical to accelerating the development of individualized immunotherapy for cancer patients.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 ObjectType-Review-3 content type line 23
ISSN:	2072-6694 2072-6694
DOI:	10.3390/cancers14174255