Trends of seasonality and age of onset in T1DM: A snapshot from Eastern India

After obtaining informed consent from parents and assent from the children, parents were interviewed and the date of birth was verified from the “birth certificate.” Multiple environmental insults may trigger autoimmune processes which may include viral infection, vitamin D deficiency, cold climate,...

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Bibliographic Details
Published in:	Indian journal of endocrinology and metabolism Vol. 24; no. 2; pp. 219 - 220
Main Authors:	Basu, Madhurima, Banerjee, Mainak, Mukhopadhyay, Pradip, Ghosh, Sujoy
Format:	Journal Article
Language:	English
Published:	Pradesh Wolters Kluwer India Pvt. Ltd 01-03-2020 Medknow Publications and Media Pvt. Ltd Medknow Publications & Media Pvt. Ltd Wolters Kluwer - Medknow Wolters Kluwer Medknow Publications
Subjects:	Age Children Diabetes Diabetes mellitus Insulin Insulin resistance Letters to the Editor Puberty Seasons Summer Type 1 diabetes Wind India
Online Access:	Get full text
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Summary:	After obtaining informed consent from parents and assent from the children, parents were interviewed and the date of birth was verified from the “birth certificate.” Multiple environmental insults may trigger autoimmune processes which may include viral infection, vitamin D deficiency, cold climate, dietary toxin, and early introduction of cow's milk. Puberty involves doubling lean body mass, increased insulin resistance,[6],[7] certain behavioral changes, and psychological issues; which may contribute additive stress on beta cells leading to a breakdown of immune tolerance and subsequent transition from preclinical phase to the clinical phase of T1DM.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	2230-8210 2230-9500
DOI:	10.4103/ijem.IJEM_72_20