Cryptococcus gattii Complex Infections in HIV-Infected Patients, Southeastern United States

• Published in: Emerging infectious diseases Vol. 24; no. 11; pp. 1998 - 2002
• Main Authors: Bruner, Kaylee T, Franco-Paredes, Carlos, Henao-Martínez, Andrés F, Steele, Gregory M, Chastain, Daniel B
• Format: Journal Article
• Language: English
• Published: United States U.S. National Center for Infectious Diseases 01-11-2018; Centers for Disease Control and Prevention
• Subjects: Anti-HIV agents; Antiviral agents; Care and treatment; CME; Complex Infections in HIV-Infected Patients, Southeastern United States; Cryptococcus; Cryptococcus gattii; Cryptococcus gattii complex; Darunavir; fungi; Health aspects; HIV (Viruses); HIV infection; HIV patients; Infection; infections; meningitis/encephalitis; Nervous system diseases; Cryptococcus gattii; United States; case series; virus; southeastern United States; Cryptococcus gattii complex; HIV/AIDS and other retroviruses; fungi; southwestern Georgia; Cryptococcus; infections; HIV-infected patients; meningitis/encephalitis; Pacific Northwest
• ISSN: 1080-6040; 1080-6059
• DOI: 10.3201/eid2411.180787

Cryptococcus gattii traditionally infects immunocompetent hosts and causes devastating pulmonary or central nervous system disease. However, this infection rarely occurs in patients infected with HIV. We report 3 cases of HIV-associated C. gattii complex infections in the southeastern United States. Detection of C. gattii in HIV-infected patients in this region warrants increased awareness of this threat to ensure appropriate diagnosis and treatment to optimize patient outcomes.