Pyruvate kinase isoform M2 (PKM2) participates in multiple myeloma cell proliferation, adhesion and chemoresistance

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Bibliographic Details
Published in:	Leukemia research Vol. 39; no. 12; pp. 1428 - 1436
Main Authors:	He, Yunhua, Wang, Yuchan, Liu, Hong, Xu, Xiaohong, He, Song, Tang, Jie, Huang, Yuejiao, Miao, Xiaobing, Wu, Yaxun, Wang, Qiru, Cheng, Chun
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 01-12-2015
Subjects:	CAM-DR Carrier Proteins - biosynthesis Carrier Proteins - genetics Carrier Proteins - physiology Cell Adhesion Cell Division Cell Line, Tumor Coculture Techniques Cyclin-Dependent Kinase Inhibitor p27 - biosynthesis Cyclin-Dependent Kinase Inhibitor p27 - genetics Drug Resistance, Neoplasm Extracellular Signal-Regulated MAP Kinases - metabolism Fibronectins Gene Expression Regulation, Neoplastic Hematology, Oncology and Palliative Medicine Humans MAPK/ERK Membrane Proteins - biosynthesis Membrane Proteins - genetics Membrane Proteins - physiology Multiple Myeloma - enzymology Multiple Myeloma - pathology Neoplasm Proteins - biosynthesis Neoplasm Proteins - genetics Neoplasm Proteins - physiology Phenotype Phosphatidylinositol 3-Kinases - metabolism Phosphorylation PI3K/Akt PKM2 Proliferation Protein Processing, Post-Translational Proto-Oncogene Proteins c-akt - metabolism RNA Interference RNA, Small Interfering - genetics Signal Transduction - physiology Stromal Cells Thyroid Hormone-Binding Proteins Thyroid Hormones - biosynthesis Thyroid Hormones - genetics Thyroid Hormones - physiology MM CAM-DR Proliferation MAPK/ERK PKM2 PI3K/Akt
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Summary:	Graphical abstract
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0145-2126 1873-5835
DOI:	10.1016/j.leukres.2015.09.019