Endosalpingiosis of Axillary Lymph Nodes: A Rare Histopathologic Pitfall with Clinical Relevance for Breast Cancer Staging

• Published in: Case reports in pathology Vol. 2016; pp. 2856358 - 5
• Main Authors: Nomani, Laila, Calhoun, Benjamin C., Biscotti, Charles V., Grobmyer, Stephen R., Sturgis, Charles D.
• Format: Journal Article
• Language: English
• Published: United States Hindawi Publishing Corporation 01-01-2016; John Wiley & Sons, Inc; Hindawi Limited
• Subjects: Care and treatment; Case Report; Case studies; Diagnosis; Lymphatic diseases
• ISSN: 2090-6781; 2090-679X
• DOI: 10.1155/2016/2856358

Establishment of accurate axillary lymph node status is of essential importance in determining both prognosis and the potential need for adjuvant therapy in patients with invasive breast cancer. Axillary lymph node heterotopias can in some cases result in overdiagnosis of metastatic disease. Nodal endosalpingiosis is perhaps the least commonly reported type of axially lymph node heterotopia. We herein illustrate a case in which second opinion pathologic interpretation combined with ancillary immunohistochemical studies allowed for a specific diagnosis of axillary nodal müllerian-type inclusions, confirming ypN0 staging and resulting in appropriate disease management and prognostication.