Prognostic Value of Heart Rate Variability in Chronic Congestive Heart Failure Secondary to Idiopathic or Ischemic Dilated Cardiomyopathy

• Published in: The American journal of cardiology Vol. 79; no. 7; pp. 978 - 980
• Main Authors: Szabó, Balázs M, van Veldhuisen, Dirk J, van der Veer, Nancy, Brouwer, Jan, De Graeff, Pieter A, Crijns, Harry J.G.M
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01-04-1997; Elsevier; Elsevier Limited
• Subjects: Biological and medical sciences; Cardiology. Vascular system; Cardiomyopathy, Dilated - complications; Cardiomyopathy, Dilated - diagnosis; Cardiomyopathy, Dilated - mortality; Death, Sudden, Cardiac - epidemiology; Electrocardiography, Ambulatory; Health risk assessment; Heart; Heart failure; Heart Failure - diagnosis; Heart Failure - etiology; Heart Failure - mortality; Heart Rate - physiology; Humans; Medical research; Medical sciences; Middle Aged; Myocarditis. Cardiomyopathies; Predictive Value of Tests; Prognosis; Proportional Hazards Models; Risk Factors; Stroke Volume; Survival Analysis; Human; Heart failure; Arrhythmia; Variability; Idiopathic; Cardiovascular disease; Coronary heart disease; Myocardial disease; Result; Vascular disease; Heart rate; Congestive hypertrophic cardiomyopathy; Ischemia; Heart disease; Myocardium; Predictive value; Complication; Evolution
• ISSN: 0002-9149; 1879-1913
• DOI: 10.1016/S0002-9149(97)00026-X

To study the prognostic value of heart rate (HR) variability in heart failure, risk assessment of clinical and HR variability parameters was performed in 159 patients with stable chronic heart failure. Besides low left ventricular ejection fraction, HR variability parameters reflecting impaired vagal tone (SDNN, pNN50) were found to predict an increased risk of cardiac death and death due to progressive pump failure.