Shorter epilepsy duration is associated with better seizure outcome in temporal lobe epilepsy surgery

• Published in: Arquivos de neuro-psiquiatria Vol. 73; no. 3; pp. 212 - 217
• Main Authors: Meguins, Lucas Crociati, Adry, Rodrigo Antônio Rocha da Cruz, Silva-Junior, Sebastião Carlos da, Araújo Filho, Gerardo Maria de, Marques, Lúcia Helena Neves
• Format: Journal Article
• Language: English
• Published: Brazil Academia Brasileira de Neurologia - ABNEURO 01-03-2015; Academia Brasileira de Neurologia (ABNEURO)
• Subjects: Adolescent; Adult; Age Factors; Aged; Child; controle das crises; duração da epilepsia; Electroencephalography; epilepsia do lobo temporal; Epilepsy, Temporal Lobe - physiopathology; Epilepsy, Temporal Lobe - surgery; Female; Humans; idade no momento da cirurgia; Magnetic Resonance Imaging; Male; NEUROSCIENCES; Postoperative Period; Prognosis; PSYCHIATRY; Retrospective Studies; Risk Factors; Seizures - physiopathology; Seizures - prevention & control; Time Factors; Treatment Outcome; Young Adult; idade no momento da cirurgia; epilepsy duration; temporal lobe epilepsy; epilepsia do lobo temporal; duração da epilepsia; seizure outcome; age at surgery; controle das crises
• ISSN: 0004-282X; 1678-4227; 1678-4227; 0004-282X
• DOI: 10.1590/0004-282X20140230

To investigate the influence of patient's age and seizure onset on surgical outcome of temporal lobe epilepsy (TLE).
A retrospective observational investigation performed from a cohort of patients from 2000 to 2012.
A total of 229 patients were included. One-hundred and eleven of 179 patients (62%) were classified as Engel I in the group with < 50 years old, whereas 33 of 50 (66%) in the group with ≥ 50 years old group (p = 0.82). From those Engel I, 88 (61%) reported epilepsy duration inferior to 10 years and 56 (39%) superior to 10 years (p < 0.01). From the total of patients not seizure free, 36 (42%) reported epilepsy duration inferior to 10 years and 49 (58%) superior to 10 years (p < 0.01).
Patients with shorter duration of epilepsy before surgery had better postoperative seizure control than patients with longer duration of seizures.