Effects of pyruvate and lactate on food intake in rat strains sensitive and resistant to dietary obesity

We have investigated the effects of peripherally administered pyruvate and lactate on the intake of high fat (HF) and low fat (LF) diets by a strain of rat either sensitive (Osborne-Mendel, OM) or resistant (SSB/P1) to high fat-induced obesity. Both pyruvate and lactate inhibited the intake of HF an...

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Bibliographic Details
Published in:	Physiology & behavior Vol. 59; no. 3; pp. 555 - 560
Main Authors:	Nagase, H., Bray, G.A., York, D.A.
Format:	Journal Article
Language:	English
Published:	Cambridge Elsevier Inc 01-03-1996 New York, NY Elsevier
Subjects:	Animals Biological and medical sciences Body Weight - drug effects Diet Diet, Fat-Restricted Dietary Fats - pharmacology Eating - drug effects Feeding. Feeding behavior Fundamental and applied biological sciences. Psychology Hepatic vagotomy High fat diet Lactates - pharmacology Lactic Acid Liver - innervation Low fat diet Male Obesity - genetics Obesity - psychology OM Rats Pyruvates - pharmacology Pyruvic Acid Rats Rats, Inbred Strains S5B/P1 Rats Species Specificity Vagus Nerve - physiology Vertebrates: anatomy and physiology, studies on body, several organs or systems Hepatic vagotomy S5B/P1 Rats OM Rats Low fat diet High fat diet Obesity Feeding behavior Rat Taxonomy Interspecific comparison Rodentia Nutrition disorder Pyruvate Lipids Metabolism Vagotomy Feeding Strain Lactates Vertebrata Mammalia Sensitivity resistance Diet Food intake Vagus nerve Nutritional status
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