The peripartum management of a patient with glutaric aciduria type 1

• Published in: Journal of clinical anesthesia Vol. 25; no. 2; pp. 141 - 145
• Main Authors: Ituk, Unyime S., MBBS, Allen, Terrence K., MBBS, Habib, Ashraf S., MBBCh, MSc, MHS
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01-03-2013; Elsevier; Elsevier Limited
• Subjects: Amino Acid Metabolism, Inborn Errors - therapy; Anesthesia; Anesthesia & Perioperative Care; Anesthesia depending on patient's condition; Anesthesia, Obstetrical - methods; Anesthesia, Spinal - methods; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy; Biological and medical sciences; Brain Diseases, Metabolic - therapy; Carnitine - therapeutic use; Cesarean Section; Female; Genetic counseling; Glucose; Glucose - administration & dosage; Glutaric aciduria type 1; Glutaryl-CoA Dehydrogenase - deficiency; Humans; Infusions, Intravenous; Kinases; Medical sciences; Metabolic disorders; Metabolism; Neuraxial anesthesia; Pain Medicine; Patients; Perioperative Care - methods; Placenta Previa - surgery; Plasma; Pregnancy; Pregnancy Complications - therapy; Prenatal Care - methods; Proteins; Surgery; Vitamin B Complex - therapeutic use; Young Adult; Pregnancy; Cesarean Section; Neuraxial anesthesia; Glutaric aciduria type 1; Metabolic disorders; Human; Nervous system diseases; Genetic disease; Carnitine; Metabolic disorder; Clinical management; Aminoacid; Anesthesia; Female; Woman; Glutaric aciduria type I; Cesarean section
• ISSN: 0952-8180; 1873-4529
• DOI: 10.1016/j.jclinane.2012.06.023

Abstract The management of cesarean delivery for a parturient with placenta previa at 36 weeks’ gestation and glutaric aciduria type 1 is presented. The management goal was to prevent encephalopathic crisis by ensuring adequate caloric intake with dextrose infusion and to provide carnitine supplementation and adequate anesthesia.