Phytoconstituents and Bioactivity of Plants of the Genus Spiraea L. (Rosaceae): A Review

• Published in: International journal of molecular sciences Vol. 22; no. 20; p. 11163
• Main Authors: Kostikova, Vera A, Petrova, Natalia V
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 16-10-2021; MDPI
• Subjects: acid; Anti-Infective Agents - chemistry; Anti-Infective Agents - pharmacology; Anti-Inflammatory Agents - chemistry; Anti-Inflammatory Agents - pharmacology; Antioxidants; Antioxidants - chemistry; Antioxidants - pharmacology; Biological activity; biotechnology; Cell Culture Techniques; Diabetes; Far East; flavonoid; Flavonoids; Fungicides; Humans; Inflammation; Lignans; Medicine, Traditional; Metabolites; Ornamental plants; Phenols; Phytochemicals - chemistry; Phytochemicals - pharmacology; Plant Extracts - chemistry; Plant Extracts - pharmacology; Review; Rosaceae; Secondary metabolites; Spiraea; Spiraea - chemistry; Steroid hormones; Subtropical zones; terpenoid; Far East; China; Russia; acid; biotechnology; biological activity; terpenoid; flavonoid; Spiraea
• ISSN: 1422-0067; 1661-6596; 1422-0067
• DOI: 10.3390/ijms222011163

The genus
L. belongs to the Rosaceae Juss. family and includes more than 100 species distributed in the temperate zone and subtropical zone of the Northern Hemisphere at the center of species diversity in East Asia. Representatives of the genus are known as ornamental plants with many forms and varieties, are widely used in conventional medicine, and have a high resource potential. This review provides information on the diversity of phenolic compounds (flavonoids, phenolcarboxylic acids, and lignans), terpenoids, alkaloids, steroids, and other classes of secondary metabolites in the species of
worldwide. The article also presents little-known and hard-to-find data published in Russian concerning
phytochemistry. The biological activities of extracts and their fractions and of individual compounds having different types of biological activity (e.g., antioxidant, antibacterial, anti-inflammatory, and antifungal) are discussed. Data about biotechnological research on representatives of the genus
are presented too. The analysis of the literature showed that further chemical and pharmacological studies on
plants are quite promising.