Development of multidrug-resistant Escherichia coli in some Egyptian veterinary farms

• Published in: Veterinary World Vol. 15; no. 2; pp. 488 - 495
• Main Authors: Samy, A A, Mansour, Asmaa S, Khalaf, Doaa D, Khairy, Eman A
• Format: Journal Article
• Language: English
• Published: India Veterinary World 01-02-2022
• Subjects: escherichia coli; food of animal origin; misuse of antibiotics; multidrug resistance; poultry; misuse of antibiotics; multidrug resistance; poultry; food of animal origin; Escherichia coli
• ISSN: 0972-8988; 2231-0916
• DOI: 10.14202/vetworld.2022.488-495

Food of animal origin is considered a major source of foodborne diseases. In this context, multidrug-resistant (MDR)
pose a serious hazard to public health due to the consumption of food contaminated with antibiotics that are used for the treatment of various bacterial infections in farm animals. Therefore, this study aimed to determine the effect of the excessive use of antibiotics on the development of MDR
strains in Egyptian poultry, dairy, and meat farms.
A total of 1225 samples were randomly collected from poultry, dairy, and meat products intended for human consumption in different governorates.
were isolated from the collected samples and subjected to biochemical identification and antibiotic sensitivity tests with antibiotics commonly used in human and veterinary medicine. Then, amoxicillin (AML)- and oxytetracycline (OT)-resistant
isolates were subjected to a polymerase chain reaction test to detect the
and
genes, respectively.
were isolated from 132 out of 350, 148 out of 350, 177 out of 350, and 35 out of 175 poultry, milk, meat, and human samples, respectively. Most of the isolates expressed multidrug resistance, and resistance genes (
and
) were detected in all the tested AML- and OT-resistant
isolates.
Foods of animal origin may represent a source of MDR
, which can be a major threat to public health.