Classical Solutions for a Nonlinear Fokker-Planck Equation Arising in Computational Neuroscience

• Published in: Communications in partial differential equations Vol. 38; no. 3; pp. 385 - 409
• Main Authors: Carrillo, José A., González, María d. M., Gualdani, Maria P., Schonbek, Maria E.
• Format: Journal Article
• Language: English
• Published: Philadelphia Taylor & Francis Group 04-03-2013; Taylor & Francis Ltd
• Subjects: 92BXX; Asymptotic properties; Blow-up; Classical solutions; Differential equations; Fokker-Planck equation; Integrate and fire neurons model; Mathematical analysis; Mathematical models; Networks; Neural networks; Neurosciences; Nonlinearity; Studies
• ISSN: 0360-5302; 1532-4133
• DOI: 10.1080/03605302.2012.747536

In this paper we analyze the global existence of classical solutions to the initial boundary-value problem for a nonlinear parabolic equation describing the collective behavior of an ensemble of neurons. These equations were obtained as a diffusive approximation of the mean-field limit of a stochastic differential equation system. The resulting nonlocal Fokker-Planck equation presents a nonlinearity in the coefficients depending on the probability flux through the boundary. We show by an appropriate change of variables that this parabolic equation with nonlinear boundary conditions can be transformed into a non standard Stefan-like free boundary problem with a Dirac-delta source term. We prove that there are global classical solutions for inhibitory neural networks, while for excitatory networks we give local well-posedness of classical solutions together with a blow up criterium. Surprisingly, we will show that the spectrum for the operator in the linear case, that corresponding to a system of uncoupled networks, does not give any information about the large time asymptotic behavior.