Stepping between Membrane Microdomains

Lateral membrane microdomains are postulated to be involved in a number of important functions in mammalian cells, such as membrane trafficking, exocytosis, endocytosis, signal transduction, and protein activity (1,2). These putative cell microdomains have been the subject of extensive research usin...

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Bibliographic Details
Published in:	Biophysical journal Vol. 108; no. 4; pp. 783 - 784
Main Author:	McIntosh, Thomas J.
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 17-02-2015 Biophysical Society The Biophysical Society
Subjects:	Actins - metabolism Actomyosin - metabolism Biochemistry Cells Chemotaxis Dictyostelium - metabolism Mammals Membrane Fluidity Membrane Lipids - chemistry Membrane Microdomains - chemistry Membranes Molecular Dynamics Simulation New and Notable Proteins Signal transduction
Online Access:	Get full text
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Summary:	Lateral membrane microdomains are postulated to be involved in a number of important functions in mammalian cells, such as membrane trafficking, exocytosis, endocytosis, signal transduction, and protein activity (1,2). These putative cell microdomains have been the subject of extensive research using a variety of biophysical and biochemical techniques, including detergent extraction (2), fluorescence microscopy (3), electron microscopy (4), fluorescence resonance energy transfer microscopy (5), fluorescence correlation spectroscopy (6), fluorescence recovery after photobleaching (7), and single-molecule tracking (8).
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Commentary-1
ISSN:	0006-3495 1542-0086
DOI:	10.1016/j.bpj.2014.12.039