Function and Application of Flavonoids in the Breast Cancer

• Published in: International journal of molecular sciences Vol. 23; no. 14; p. 7732
• Main Authors: Park, Min Yeong, Kim, Yoonjung, Ha, Sang Eun, Kim, Hun Hwan, Bhosale, Pritam Bhangwan, Abusaliya, Abuyaseer, Jeong, Se Hyo, Kim, Gon Sup
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 13-07-2022; MDPI
• Subjects: Anomalies; Antioxidants; Apoptosis; Autophagy; Breast; Breast cancer; Breast Neoplasms - drug therapy; Breast Neoplasms - genetics; Cancer therapies; Cell cycle; Cell growth; Chemotherapy; Endocrine therapy; Enzymes; Female; flavonoid; Flavonoids; Flavonoids - pharmacology; Flavonoids - therapeutic use; Humans; Kinases; Medical prognosis; Metastasis; Proteins; Radiation therapy; Radiation tolerance; Review; Surgery; Tumors; apoptosis; breast cancer; flavonoid
• ISSN: 1422-0067; 1661-6596; 1422-0067
• DOI: 10.3390/ijms23147732

Breast cancer is one of the top causes of death, particularly among women, and it affects many women. Cancer can also be caused by various factors, including acquiring genetic alteration. Doctors use radiation to detect and treat breast cancer. As a result, breast cancer becomes radiation-resistant, necessitating a new strategy for its treatment. The approach discovered by the researchers is a flavonoid, which is being researched to see if it might help treat radiation-resistant breast cancer more safely than an approved medicine already being used in the field. As a result, this study focuses on the role of flavonoids in breast cancer suppression, breast cancer gene anomalies, and the resulting apoptotic mechanism.