A male patient with malignant lymphoma and thyroid papillary carcinoma after pediatric renal transplantation

• Published in: Clinical and experimental nephrology Vol. 14; no. 1; pp. 94 - 96
• Main Authors: Motoyama, Osamu, Takasu, Jiro, Kawamura, Takeshi, Aikawa, Atushi, Shigetomi, Yukari, Nara, Chiharu, Ohara, Akira, Iitaka, Kikuo, Hasegawa, Akira
• Format: Journal Article
• Language: English
• Published: Japan Springer Japan 01-02-2010; Springer Nature B.V
• Subjects: Carcinoma, Papillary - drug therapy; Carcinoma, Papillary - virology; Case Report; Child; Herpesvirus 4, Human - isolation & purification; Humans; Kidney Transplantation - adverse effects; Lymphoma - drug therapy; Lymphoma - virology; Male; Medicine; Medicine & Public Health; Nephrology; Thyroid Neoplasms - virology; Thyroidectomy; Urology; Young Adult; Renal transplantation; Malignant lymphoma; Thyroid papillary carcinoma; Child; Epstein–Barr virus
• ISSN: 1342-1751; 1437-7799
• DOI: 10.1007/s10157-009-0210-6

A 6-year-old boy received renal transplantation and was treated with methylprednisolone, cyclosporine A and mizoribine. He developed Epstein–Barr virus-associated malignant lymphoma at 10 years and thyroid papillary carcinoma at 20 years of age. Chemotherapy for the malignant lymphoma was done after withdrawal of cyclosporine A and mizoribine, and thyroidectomy was performed for thyroid carcinoma. He was well and his serum creatinine was 1.0 mg/dl at 22 years of age. To our knowledge, no pediatric renal transplant recipient who had thyroid carcinoma or two different types of tumor has been reported in Japan.