Maternal protein-energy and energy-restricted diets during lactation possibly could program folliculogenesis and the ovarian expression of leptin and its different isoform receptors in rats

• Published in: Fertility and sterility Vol. 92; no. 5; pp. 1755 - 1757
• Main Authors: da Silveira Cavalcante, Fernanda, M.D, Gombar, Flávia Meireles, U.S, Ferreira, Rafaela Veiga, M.D, da Silva Faria, Tatiane, Ph.D, Costa, Waldemar Silva, Ph.D, Sampaio, Francisco José Barcellos, Ph.D, da Fonte Ramos, Cristiane, Ph.D
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01-11-2009
• Subjects: Animals; Animals, Newborn; Caloric Restriction - adverse effects; Caloric Restriction - veterinary; Diet - adverse effects; Dietary Proteins - pharmacology; Energy Intake - physiology; Female; Internal Medicine; Lactation - drug effects; Lactation - physiology; Leptin - genetics; Leptin - metabolism; Maternal Nutritional Physiological Phenomena - drug effects; Maternal-Fetal Exchange; Obstetrics and Gynecology; Oogenesis - drug effects; Oogenesis - genetics; Oogenesis - physiology; Ovarian Follicle - drug effects; Ovarian Follicle - metabolism; Ovarian Follicle - physiology; Ovary - drug effects; Ovary - metabolism; Pregnancy; Protein Isoforms - genetics; Protein Isoforms - metabolism; Rats; Rats, Wistar; Receptors, Leptin - genetics; Receptors, Leptin - metabolism
• ISSN: 0015-0282; 1556-5653
• DOI: 10.1016/j.fertnstert.2009.05.037

Both protein-energy and energy-restricted diets during lactation program the ovarian function of the rat offspring, leading to a reduction of folliculogenesis, possibly as the consequence of the altered expression of leptin and its isoform receptor genes.