Rapid glucose detection by surface enhanced Raman scattering spectroscopy

An approach to reject stray light and improve glucose adsorption was presented. With a self-assembled monolayer (SAM) and a confocal optical configuration applied in this approach, the adsorption and signal to noise ratio (SNR) have been improved respectively. Our experimental results demonstrated t...

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Bibliographic Details
Published in:	Journal of nanoscience and nanotechnology Vol. 9; no. 4; p. 2660
Main Authors:	Yang, Lanying, Du, Chunlei, Luo, Xiangang
Format:	Journal Article
Language:	English
Published:	United States 01-04-2009
Subjects:	Adsorption Glucose - analysis Glucose - chemistry Hexanols - chemical synthesis Hexanols - chemistry Nanospheres - chemistry Polystyrenes - chemistry Silver - chemistry Spectrum Analysis, Raman - instrumentation Spectrum Analysis, Raman - methods Sulfhydryl Compounds - chemical synthesis Sulfhydryl Compounds - chemistry Surface Properties Time Factors
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Summary:	An approach to reject stray light and improve glucose adsorption was presented. With a self-assembled monolayer (SAM) and a confocal optical configuration applied in this approach, the adsorption and signal to noise ratio (SNR) have been improved respectively. Our experimental results demonstrated that the surface enhanced Raman scattering (SERS) spectroscopy with 9 feature peaks for 100 mM aqueous glucose is successfully obtained in a dry environment in response time as fast as 40 s only. This approach could improve glucose detection in response time and sensitivity effectively in atmosphere environment.
ISSN:	1533-4880
DOI:	10.1166/jnn.2009.454